Leishmania turns down the heat

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Down-Regulation of T Cell Function by Heat Shock-Induced Excretory Factor of Leishmania Major

Background: Despite demonstration of molecular and biochemical changes induced by heat shock on Leishmania, the immunological importance of such changes has not been elucidated.  Objective: Studying the effect of two excretory factors prepared under heat shock and ambient temperature from Leishmania major on Balb/c splenocytes function.  Methods: The parasites were cultured at 25°C and then sub...

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down-regulation of t cell function by heat shock-induced excretory factor of leishmania major

background: despite demonstration of molecular and biochemical changes induced by heat shock on leishmania , the immunological importance of such changes has not been elucidated.   objective: studying the effect of two excretory factors prepared under heat shock and ambient temperature from leishmania major on balb/c splenocytes function.   methods: the parasites were cultured at 25 ° c and the...

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ژورنال

عنوان ژورنال: Nature Reviews Microbiology

سال: 2011

ISSN: 1740-1526,1740-1534

DOI: 10.1038/nrmicro2626